Monday, February 29, 2016

Forgotten fossil reveals growth potential of carnivorous dinosaurs

"Our study shows how museums still play an important role in preserving specimens of primary scientific value," said study co-author Andrea Cau. By Brooks Hays   |   Feb. 29, 2016 at 10:32 AM

A rendering offers an idea of how large abelisaurs were. Photo by ICL
LONDON, Feb. 29 (UPI) -- After re-examining a fossilized femur bone belonging to an abelisaur specimen, researchers can say with more certainty how large these fearsome predators could become.
Based on their analysis, researchers at Imperial College London believe the femur belonged to an abelisaur weighing nearly two metric tons and stretching nine meters, or almost 30 feet. Those dimensions make it one of the largest abelisaurs ever found.
The new research was detailed in the journal PeerJ.
"Smaller abelisaur fossils have been previously found by paleontologists, but this find shows how truly huge these flesh eating predators had become," researcher Alessandro Chiarenza, study co-auhtor, said in a press release. "Their appearance may have looked a bit odd as they were probably covered in feathers with tiny, useless forelimbs, but make no mistake they were fearsome killers in their time."
Abelisauridae dinosaurs made up for their tiny forelimbs and odd appearance with massive hindquarters and deadly sharp teeth. They thrived in what is now northern Africa some 95 million years ago, though abelisaur fossils have been dated as far back as 170 million years ago and as recently as 66 million years ago.
The femur was originally found in a Moroccan deposit known as Kem Kem Beds -- famous for its abundance of predatory dino bones. The site has confounded researchers who believe it would have been impossible for so many carnivorous dinosaurs to coexist in such tight quarters.
New analysis suggests the sometimes violent geologic conditions that created Kem Kem Beds may have also mixed up the strata and chronology of the fossil record.
Other sites suggest abelisaur were inland hunters, somewhat separated from their closest cousins, who preferred to hunt fish near lakes and rivers.
"This fossil find, along with the accumulated wealth of previous studies, is helping to solve the question of whether abelisaurs may have co-existed with a range of other predators in the same region," Chiarenza explained. "Rather than sharing the same environment, which the jumbled up fossil records may be leading us to believe, we think these creatures probably lived far away from one another in different types of environments."
The fossil was not recently unearthed, but had been sitting in a museum drawer for several decades -- further proof that closeted collections hide nearly as many secrets as untouched earth.
"While palaeontologists usually venture to remote and inaccessible locations, like the deserts of Mongolia or the Badlands of Montana," added Andrea Cau, study co-author and researcher at the University of Bologna, "our study shows how museums still play an important role in preserving specimens of primary scientific value, in which sometimes the most unexpected surprises can be discovered."

Sunday, February 21, 2016

Turmeric: Is This 'Miracle Food' the Real Deal? Here's What the Research Says

http://www.stack.com/ 



Unless you've been living under a rock for the past three months, you've probably heard about turmeric. If not, here's a quick rundown: Turmeric is a plant in the ginger family that's native to southwest India. Its root can be boiled, ground and baked to produce an orangish-yellowish powder. This powder, often referred to as ground turmeric or turmeric powder, has been a staple of Indian and Pakistani cuisine for thousands of years. Now, many Americans are also embracing it. So, why are we suddenly obsessed with this ancient spice?

Because it's being labeled across the internet as an incredibly powerful "superfood." Google "turmeric health benefits" and you'll find thousands of articles claiming turmeric can do everything under the sun. If you believe everything you read, turmeric can supposedly:
  • whiten teeth
  • reduce wrinkles
  • relieve pain
  • thicken hair
  • treat and prevent multiple forms of cancer
  • prevent Alzheimer's
  • increase weight loss
  • treat depression
  • improve sleep
  • pretty much anything else you could ever want
Pretty crazy, right? Well, don't go out and buy drums of turmeric quite yet. It's not uncommon for the benefits of trendy foods to get exaggerated, only to fade from the limelight when people realize those benefits are mostly hot air. That's why STACK dove into the research to see if turmeric really deserves to be the next big thing in nutrition.

The Secret Ingredient

 

Turmeric Powder

Before we address the research, let's check out the basic nutritional profile of ground turmeric. One tablespoon contains 24 calories, .7 grams of fat, 1.4 grams of fiber and .5 grams of protein. In terms of the major vitamins and minerals, it contains a solid amount of iron but not much else. So the basic nutritional facts are pretty pedestrian. If that's the case, why is turmeric getting so much hype?
The answers lies in curcumin, a powerful antioxidant found almost exclusively in turmeric. Much of the research into turmeric's health benefits focus on its curcumin content. When it comes to the purported benefits of turmeric, curcumin is key.
How much curcumin is in ground turmeric?
According to a 2006 study published in the journal Nutrition and Cancer, pure turmeric powder averages 3.14% curcumin by weight. So if you eat 100 grams of pure turmeric powder, you will consume about 3.14 grams of curcumin. A tablespoon of turmeric powder measures 17 grams, containing roughly .57 grams (or 570 mg) of curcumin. That's a solid amount, but downing tablespoons of ground turmeric powder can be unpleasant—which is why many people take turmeric in the form of a capsule supplement.
Now that we know about the importance of curcumin, let's check out the research.

Can Turmeric Help Reduce Inflammation?

Ground Turmeric


Inflammation is the body's natural response to injury, infection or disease. Its purpose is to protect the body and let it heal. But chronic inflammation can become a health risk. Many common conditions—such as asthma and arthritis—are classified as "inflammatory," and inflammation can contribute to more life-threatening diseases like cancer and cardiovascular disease. So if turmeric could help reduce inflammation, that would be an awesome benefit. But is it true?
RELATED: Three Powerful Health Benefits of Turmeric
The research says yes. Examine, an independent site that collates scientific research and disseminates information on supplementation and nutrition, points to five separate studies regarding curcumin's effects on inflammation before concluding that "there appears to be a decrease in disease states or conditions characterized by inflammation associated with curcumin ingestion" and that curcumin "does not appear to be too discriminatory in which inflammatory states it benefits."
The average age of the subjects varied widely among the studies, and curcumin was found to reduce inflammation related to a wide variety of conditions, including osteoarthritis, diabetic nephropathy and lichen planus (a skin disease).

Can Turmeric Change Body Composition?

 

Turmeric

Millions of Americans are overweight. And millions of Americans desire to change their bodies for the better. So the promise that turmeric can potentially aid in fat loss is certainly appealing. But does the research back it up?
Not quite. There currently isn't enough data to support the idea that turmeric has a significant effect on body composition. A 2009 animal study found that dietary curcumin could potentially inhibit the spread of fat tissue, but not  enough high-quality research is yet available to reach a conclusion on this topic.

Can Turmeric Be Used as a Pain Reliever?

 

Turmeric


One of turmeric's most interesting reported benefits is pain relief. Instead of popping a Tylenol, you could just down some turmeric. It's intriguing, sure. But is it true?
It looks likely. There haven't been a ton of studies on turmeric's role as a pain reliever, but what's available is encouraging. Examine writes, "there appear to be decreases in pain associated with curcumin at higher doses (400-500 mg) which extend to post-operative, arthritic and general pain symptoms. This does seem comparable to 2g of acetaminophen in potency."
Acetaminophen is the major active ingredient in Tylenol and many generic pain relievers, so that's a pretty impressive result.

Can Turmeric Help Battle or Even Prevent Forms of Cancer?

 

Turmeric


Perhaps the most intriguing purported benefit of turmeric is its ability to battle cancer. It sounds too good to be true, but a growing amount of research suggests that curcumin can help fight this all-too-common disease.
According to the University of Maryland Medical Center, "there has been a great deal of research on turmeric's anti-cancer properties, but results are still very preliminary. Evidence from test tube and animal studies suggests that curcumin may help prevent or treat several types of cancers, including prostate, breast, skin, and colon cancer. Tumeric's preventive effects may relate to its antioxidant properties, which protect cells from damage. More research is needed."
Yes, more research is needed, but early results are encouraging regarding curcumin's role in battling cancer.

Can Turmeric Help Prevent Heart Disease?

 

Turmeric


According to the CDC, one in every four deaths in the United States can be attributed to heart disease. Could turmeric help curb this massive public health issue?
RELATED: Heart-Healthy Foods for Athletes
It's too early to tell. Some animal studies have found that curcumin could help improve your cholesterol profile and thus reduce your risk of blocked arteries (which lead to heart attacks and stroke), but the same results have not yet been achieved in human studies. Turmeric could potentially help prevent heart disease, or it could have no discernible effect—we'll just have to wait for more research.

Can Turmeric Help Treat Depression?

Turmeric


According to the Anxiety Disorders Association of America, depression affects nearly 15 million Americans in any given year. Could turmeric help boost the mood of those suffering with depression?
Research has been sparse but encouraging. One study found that taking 500 mg of curcumin twice a day (roughly equivalent to two tablespoons of pure powdered turmeric) helped depressed subjects reduce their symptoms as well as Fluoxetine, a popular anti-depressant medication frequently marketed under the name "Prozac." However, no placebo group was used for comparison in the study.

Can Turmeric Make Me More Attractive?

 

Ground Turmeric


Turmeric's supposed benefits also include beautification: whiter teeth, clearer skin and thicker hair. They all sound great, but the only one supported by research is clearer skin.
RELATED: Just a Spoonful a Day of These 5 Foods Can Boost Your Health
Several studies have found that ground turmeric helps protect the skin from UV rays, reduce the appearance of dark spots, reduce acne, prevent wrinkles and help heal wounds. So the idea that turmeric can help improve the health and appearance of your skin certainly sounds valid.
However, claims like whiter teeth and thicker hair aren't backed by the same amount of research. It's possible that turmeric (more specifically, curcumin) could help confer those benefits, but the research is extremely limited at this point in time.

The Verdict

 

Turmeric


It's not unusual for the benefits of hip, trendy foods to get totally overblown. However, in the case of turmeric, a solid amount of research backs up many of its purported health benefits. More research is needed before concrete conclusions are reached, but even in areas where the research has been sparse—such as pain relief—early results have been encouraging. You shouldn't toss out the contents of your medicine cabinet in favor of turmeric, but it really does seem likely to have impressive capabilities.
There has yet to be a consensus on the best way to ingest turmeric and/or curcumin. The human body has been found capable of consuming 8 grams of curcumin a day without adverse affects, so overdosing shouldn't be a major concern. Whether you take it as a supplement or use it to spice up your food, you should strive to combine turmeric with a source of fat and/or black pepper. These greatly increase the absorption rate of curcumin, and many turmeric or curcumin supplements contain them.

Topics: DIET
 
Brandon Hall Brandon Hall - Brandon Hall is an Assistant Content Director for STACK. He graduated from Lafayette College, where he played football and graduated with a Bachelor's degree in English.

Wednesday, February 17, 2016

Humans and Neanderthals had sex a lot earlier than scientists thought

http://www.theverge.com/

Some humans may have left Africa over 100,000 years ago

(Hairymuseummatt / Dr.Mike Baxter)
An analysis of the genome of a Siberian Neanderthal, published today in Nature, reveals for the first time that humans contributed DNA to the Neanderthal genome about 100,000 years ago; that's 50,000 years earlier than the previous estimate. The finding points to an earlier departure from Africa for our human ancestors.
Between 1 and 7 percent of the Siberian Neanderthal’s genome was human — inherited from people who migrated out of Africa. That suggests humans and Neanderthals interbred several times. But it also alters our understanding of human history. Since Neanderthals didn’t make it to Africa, humans must have left about 50,000 years earlier than evolutionary biologists had previously estimated. And that's big news, says Sergi Castellano, an evolutionary biologist at the Max Planck Institute for Evolutionary Anthropology in Germany and a co-author of the study. This is "the first piece of genetic evidence" that some modern humans "were already out of Africa" 100,000 years ago, he says.
Humans left their mark on Neanderthals, too
Previous genetic analyses have revealed that humans interbred with Neanderthals less than 65,000 years ago, outside of Africa. As a result, Europeans and Asians inherited between 1 and 4 percent of their DNA from Neanderthals. And that DNA still has an effect on humans today; just last week scientists linked Neanderthal DNA to a wide range of human health conditions, including depression and nicotine addiction.
But until now, what researchers knew about Neanderthal-human interactions came from studying the flow of genes from Neanderthals to humans — and not the other way around. That's mostly because researchers didn't have the kinds of technologies or the appropriate Neanderthal DNA samples that would allow them to search in the opposite direction. This is the first time that scientists have been able to find evidence that humans left their genetic mark on Neanderthals as well, says Laurent Frantz, an evolutionary biologist at the University of Oxford who didn't work on the study.
A Siberian Neanderthal with human DNA
To arrive at these conclusions, Castellano and his team searched the complete genome of a Neanderthal discovered in a Siberian Cave in 2010. They found that certain regions of the Neanderthal's genome was closely related to those found in African human populations today. To estimate the timing of the interbreeding event, the researchers performed a statistical analyses based on the size and the clustering of the DNA fragments. This technique works because researchers know that when animals reproduce, their genetic material mixes with that of other animals; this causes individual DNA fragments belonging to one individual to break into smaller pieces as they're passed down through generations. In this particular case, the technique revealed that the Siberian Neanderthal's ancestors interbred with humans some 100,000 years ago.
Neanderthal toe bone (Bence Viola)
The researchers verified their findings by looking at the genome of a Denisovan — a member of an extinct human species that split off from Neanderthals some 380,000 years ago, after Neanderthals became a subspecies distinct from modern humans. Because Denisovans are more closely related to Neanderthals than they are to humans, their genomes can help scientists figure out the kinds of genetic mutations that are typical of these human subspecies. The analysis showed no evidence of the human DNA fragments in the Denisovan's genome, which suggests that these genetic elements were introduced in the Siberian Neanderthal's genome after Denisovans and Neanderthals evolved away from each other.
Castellano and his team also compared genetic material on chromosome 21 for the Siberia Neanderthal and two different populations of European Neanderthals. The scientists found no evidence of human integration in the European samples, which means that ancestors of the introduction of human DNA into the Siberia Neanderthal probably happened after the Siberian population branched off from the European Neanderthals,  around 110,00 years ago.
"This is a big milestone."
The study "doesn't change what we knew before; it's building on it," Frantz says. Instead, it gives scientists a better understanding of how many times human and Neanderthals met. "This is a big milestone," he says.
Sarah Tishkoff, an evolutionary biologist at University of Pennsylvania who didn't work on this study, agrees. "This is really exciting work because it changes what we thought about human evolutionary history." But she also says that the the comparison of chromosome 21 means that researchers could be missing signs of human DNA integration in the rest of the European genomes. In addition, the study doesn't actually reveal much about the interbreeding event itself. Even though the Neanderthal in the study was found in Siberia, the human-neanderthal interactions probably occurred further south, Tishkoff says. But where exactly those interactions happened is a mystery. The fate of these adventurous humans is also unclear, Frantz says. "The population is probably partly extinct, and partly integrated in many different populations across the world."
The study raises a ton of questions, but for now the findings suggest that what we thought we knew about humans and Neanderthals is just one tiny piece of the puzzle. "There could have been multiple [human] migrations coming out of Africa, and some groups just didn't make it," Tishkoff says. Research like this helps "paint a picture of what the ancestry was, not just of modern humans, but of Neanderthals; and that picture was more complex than we thought."

Friday, February 5, 2016

Mystery invaders conquered Europe at the end of last ice age

https://www.newscientist.com

DNA was taken from ancient human bones, like this skull, from the Dolnte Vestonice burial site in the Czech Republic


DNA was taken from ancient human bones, like this skull, 
from the Dolnte Vestonice burial site in the Czech Republic

L. Lang
Europe went through a major population upheaval about 14,500 years ago, at the end of the last ice age, according to DNA from the bones of hunter-gatherers.
Ancient DNA studies published in the last five years have transformed what we know about the early peopling of Europe. The picture they paint is one in which successive waves of immigration wash over the continent, bringing in new people, new genes and new technologies.
These studies helped confirm that Europe’s early hunter-gatherers – who arrived about 40,000 years ago – were largely replaced by farmers arriving from the Middle East about 8000 years ago. These farmers then saw an influx of pastoralists from the Eurasian steppe about 4500 years ago, meaning modern Europe was shaped by three major population turnover events.

Waves of immigration

The latest study suggests things were even more complicated. About 14,500 years ago, when Europe was emerging from the last ice age, the hunter-gatherers who had endured the chilly conditions were largely replaced by a different population of hunter-gatherers.
Exactly where this new population came from is still unclear, but it seems likely that they came from warmer areas further south. “The main hypothesis would be glacial refugia in south-eastern Europe,” says Johannes Krause at the Max Planck Institute for the Science of Human History in Jena, Germany, who led the analysis.
As conditions improved, it was these southern hunter-gatherers who took advantage and migrated into central and northern Europe, he says – meaning there was a genetic discontinuity with the hunter-gatherer populations that had lived there earlier.


2nd_107773
Martin Frouz
His team analysed mitochondrial DNA extracted from 55 ancient Europeans, the oldest of whom lived 35,000 years ago – during the Pleistocene – and the youngest just 7000 years ago, during the Holocene. Previous studies focused largely on the Holocene, looking at human remains from the last 10,000 years.
“This is the first glimpse at Pleistocene population dynamics in Europe,” says Krause. “Little has been done on this older material, mostly due to lower abundance of material and lesser preservation due to age.”
“The population turnover after 14,500 years ago was completely unexpected,” says Iosif Lazaridis at the Harvard Medical School in Boston. “It seems that the hunter-gatherers of Europe braved the worst of the ice age during the last glacial maximum but were then replaced when the ice age had begun to subside.”

Europe’s unusual history

The picture is not yet clear, however, as the study only looked at mitochondrial DNA sequences, rather than the longer nuclear DNA of other studies. “Mitochondrial DNA tells only part of the story of a population,” says Lazaridis. It is important to try to extract nuclear sequences from the Pleistocene-aged skeletons to find out more about this earlier population turnover, he says.
The work also may solve a long-standing mystery of why a certain genetic signature is missing in people of European ancestry. All people today are members of one of a relatively small number of distinct groups based on their mitochondrial DNA, which is passed down the maternal line. The distribution of people in each group gives us a sense of how humans spread across the world in prehistory.
It always seemed that Europe had a very unusual history of colonisation because one major haplogroup – the M clade – is almost entirely missing, despite being very common across Asia and even found in Native Americans. Instead, another major haplogroup – the N clade – is most common.
“Some authors had argued that the M and N haplogroups represented two different dispersal events from Africa,” says Toomas Kivisild at the University of Cambridge.
But Krause and his colleagues found that the M clade might actually have been common in Europe before the population turnover 14,500 years ago: three of the 18 most ancient humans they studied belonged to the M clade.
This suggests that the initial colonisation of Europe and Asia may have involved the same ancient population – and that the M group was actually lost in Europe much later, perhaps connected in some way to the mystery upheavals 14,500 years ago.
Journal reference: Current Biology, DOI: 10.1016/j.cub.2016.01.037
Read more: The three ancestral tribes that founded Western civilisation

 http://arstechnica.com/

Scientific Method / Science & Exploration


There was a massive population crash in Europe over 14,500 years ago

New evidence shows a whole group of Europeans vanished, replaced by people of unknown origins.


Europe wasn't a very hospitable place fifteen millennia ago. The westernmost landmass of the Eurasian continent had endured a long ice age, with glaciers stretching across northern Europe and into the region we now call Germany. But suddenly, about 14,500 years ago, things started to warm up quickly. The glaciers melted so fast around the globe that they caused sea levels to rise 52 feet in just 500 years. Meanwhile, the environment was in chaos, with wildlife trying vainly to adjust to the rapid fluctuations in temperature. Humans weren't immune to the changes, either.
A new, comprehensive analysis of ancient European DNA published today in Current Biology magazine by an international group of researchers reveals that this period also witnessed a dramatic shift in the human populations of Europe. Bloodlines of hunter-gatherers that had flourished for thousands of years disappeared, replaced with a new group of hunter-gatherers of unknown origin.
Researchers discovered this catastrophic population meltdown by sequencing the mitochondrial DNA of 35 people who lived throughout Europe between 35 and 7 thousand years ago. Mitochondrial DNA is a tiny amount of genetic material that's inherited virtually unchanged via the maternal line, and thus it serves as a good proxy for relatedness over time. Two people from the same maternal stock share almost the same mitochondrial DNA, even if separated by thousands of years, because this kind of DNA evolves very slowly.
It's long been known that two such related groups, called M clade and N clade, poured out of Africa and across the Eurasian continent about 55 thousand years ago. Some of these people wandered so far that they even made it to Australia, eventually. And yet something rather odd happened to the people of Europe. Only members of the N clade survived into the present day, while Asia, Australia, and the Americas are full of the offspring of both N and M. Until the new study in Current Biology, scientists believed that the most likely explanation was that roughly 45 thousand years ago, Europe was colonized solely by the N clade, while both clades settled elsewhere around the world.
But thanks to sequencing the mitochondrial DNA in those 35 ancient people, the researchers uncovered something previously unknown. There were, in fact, people from the M clade alive in Europe as recently as 25 thousand years ago. But something happened to wipe them out during the cold, dry glacial maximum that gripped the world between 25 and 14.5 thousand years ago.

Enlarge / In this image, you can see the clades of the people
 who the team sequenced, and how they fared over time. The
 R and U clades are all descended from the N clade. Note that
 M is present until 25 thousand years ago, when the ice age begins.
Current Biology
There are obvious reasons why Europeans might have suffered a population bottleneck during the ice age, or the Last Glacial Maximum. Food was scarce, and once-fecund habitats became unlivable. Groups that once roamed the wide-open fields of Europe retreated into small refuges, separated by walls of ice or frozen drought wastelends created when glaciation locks up atmospheric water. The researchers believe that the M clade, whose members were found far to the north, may have slowly died out during that period. After the glaciers retreated, the survivors were replaced by a new N-related population from elsewhere on the continent.
Write the researchers:
The potential impact of climatic events on the demography, and thus the genetic diversity of early Europeans, has previously been difficult to quantify, but it likely had consequences for the relative components of ancient ancestry in modern-day populations. Our demographic modeling reveals a dynamic history of hunter-gatherers, including a previously unknown major population shift during the Late Glacial interstadial (the BøllingAllerød, 14.5 ka). Under our best-fitting model, the small initial founder population of Europe slowly grows up until 25 ka and survives with smaller size in LGM [Last Glacial Maximum] climatic refugia (25–19.5 ka) before re-expanding as the ice sheets retract. Although this model supports population continuity from pre- to post-LGM, the genetic bottleneck is consistent with the apparent loss of hg M in the post-LGM. Globally, the early warming phases of the Late Glacial are strongly associated with substantial demographic changes, including extinctions of several megafaunal species and the first expansion of modern humans into the Americas. In European hunter-gatherers, our model best explains this period of upheaval as a replacement of the post-LGM maternal population by one from another source.
Essentially, an entire genetic line in Europe was wiped out by climate change. You might say that today's European population still bears the scars of an ancient ice age in its mitochondrial DNA.
Current Biology, 2016. DOI: 10.1016/j.cub.2016.01.037.

Why Did Ancient Europeans Just Disappear 14,500 Years Ago?

LiveScience.com
Why Did Ancient Europeans Just Disappear 14,500 Years Ago? 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 The skull of a man who lived between 36,200 
and 38,700 years ago in Kostenki in western Russia.
 
Some of Europe's earliest inhabitants mysteriously vanished toward the end of the last ice age and were largely replaced by others, a new genetic analysis finds.
The finds come from an analysis of dozens of ancient fossil remains collected across Europe.
The genetic turnover was likely the result of a rapidly changing climate, which the earlier inhabitants of Europe couldn't adapt to quickly enough, said the study's co-author, Cosimo Posth, an archaeogenetics doctoral candidate at the University of Tübingen in Germany.
 [Top 10 Mysteries of the First Humans]
The temperature change around that time was "enormous compared to the climactic changes that are happening in our century," Posth told Live Science. "You have to imagine that also the environment changed pretty drastically."
A twisted family tree
Europe has a long and tangled genetic legacy. Genetic studies have revealed that the first modern humans who poured out of Africa, somewhere between 40,000 and 70,000 years ago, soon got busy mating with local Neanderthals. At the beginning of the agricultural revolution, between 10,000 and 12,000 years ago, farmers from the Middle East swept across Europe, gradually replacing the native hunter-gatherers. Around 5,000 years ago, nomadic horsemen called the Yamnaya emerged from the steppes of Ukraine and intermingled with the native population. In addition, another lost group of ancient Europeans mysteriously vanished about 4,500 years ago, a 2013 study in the journal Nature Communications found.
But relatively little was known about human occupation of Europe between the first out-of-Africa event and the end of the last ice age, around 11,000 years ago. During some of that time, the vast Weichselian Ice Sheet covered much of northern Europe, while glaciers in the Pyrenees and the Alps blocked east-west passage across the continent.
Lost lineages
To get a better picture of Europe's genetic legacy during this cold snap, Posth and his colleagues analyzed mitochondrial DNA — genetic material passed on from mother to daughter — from the remains of 55 different human fossils between 35,000 and 7,000 years old, coming from across the continent, from Spain to Russia. Based on mutations, or changes in this mitochondrial DNA, geneticists have identified large genetic populations, or super-haplogroups, that share distant common ancestors.
"Basically all modern humans outside of Africa, from Europe to the tip of South America, they belong to these two super-haplogroups that are M or N," Posth said. Nowadays, everyone of European descent has the N mitochondrial haplotype, while the M subtype is common throughout Asia and Australasia.
The team found that in ancient people, the M haplogroup predominated until about 14,500 years ago, when it mysteriously and suddenly vanished. The M haplotype carried by the ancient Europeans, which no longer exists in Europe today, shared a common ancestor with modern-day M-haplotype carriers around 50,000 years ago.
The genetic analysis also revealed that Europeans, Asians and Australasians may descend from a group of humans who emerged from Africa and rapidly dispersed throughout the continent no earlier than 55,000 years ago, the researchers reported Feb. 4 in the journal Current Biology.
Time of upheaval
The team suspects this upheaval may have been caused by wild climate swings.
At the peak of the ice age, around 19,000 to 22,000 years ago, people hunkered down in climactic "refugia," or ice-free regions of Europe, such as modern-day Spain, the Balkans and southern Italy, Posth said. While holdouts survived in a few places farther north, their populations shrank dramatically.
Then around 14,500 years ago, the temperature spiked significantly, the tundra gave way to forest and many iconic beasts, such as woolly mammoths and saber-toothed tigers, disappeared from Eurasia, he said.
For whatever reason, the already small populations belonging to the M haplogroup were not able to survive these changes in their habitat, and a new population, carrying the N subtype, replaced the M-group ice-age holdout, the researchers speculate.
Exactly where these replacements came from is still a mystery. But one possibility is that the newer generation of Europeans hailed from southern European refugia that were connected to the rest of Europe once the ice receded, Posth speculated. Emigrants from southern Europe would also have been better adapted to the warming conditions in central Europe, he added.


40 million years before butterflies existed, this creature evolved with strikingly similar looks

 https://www.washingtonpost.com/

Speaking of Science
Before butterflies, there were Kalligrammatid lacewings — winged insects that took butterfly-like form at least 40 million years before the modern bugs first came on the scene. But the remarkably butterflyesque species Oregramma illecebrosa, described in a study published Wednesday in Proceedings of the Royal Society B, isn't a butterfly ancestor: Other members of its lineage went on to become entirely different sorts of insects. Instead, this striking similarity is a case of convergent evolution — the same shapes, patterns and perhaps even behaviors came about twice, totally independently.
The findings come thanks to some especially well-preserved fossils found in northeastern China, which allowed researchers to study the ancient insects more closely than ever before.
"They've been known for about 100 years, but in the 1960s there were some specimens that made people say, gosh, these really look like butterflies," Smithsonian paleoecologist Conrad Labandeira, lead author on the study, told The Washington Post. "But we knew they were unrelated. That's where it stood for some 55 years."
But once Labandeira and his team — an international collaboration of scientists — got a hold of the Chinese fossils, things got much more interesting. The resemblance is so strong that even experts were fooled at a distance: Labandeira recalls a colleague from the entomology department assuming the fossil on the table was a butterfly from 20 feet away.
"When I told him to come closer, and he looked again, his jaw dropped," Labandeira said.
One of the more remarkable similarities is superficial in nature: The spots seen on the Oregramma illecebrosa fossils are nearly identical to patterns found on owl butterflies today. These so-called eye spots mimic the peepers of a large bird, scaring off predators that might otherwise make a quick snack of a delicate butterfly.
It's thought that Oregramma illecebrosa last shared a common ancestor with modern butterflies more than 320 million years ago. The fact that two quite unrelated insects developed these markings millions of years apart from one another is a perfect example of convergent evolutionOregramma illecebrosa might not have shared space with owls, but plenty of big-eyed creatures — perhaps even dinosaurs, the prominent predators of the Jurassic period — could have served as inspiration for the markings. An Oregramma illecebrosa would have had a better chance of surviving dino dinnertime if it could pass itself off as a bigger animal, and over time — as faux-eyed insects continued to breed more successfully than those without the markings — the patterns would become more complex.
Then, millions of years later, an unrelated group of insects did the exact same thing. What worked well in the Jurassic still works well today.
But there are signs that these ancient bugs shared behavioral traits with modern butterflies, too: They had modified hairs on their legs for collecting pollen, just as modern butterflies do. And they even had long proboscises, which modern butterflies use to suck nectar from flowers — even though flowering plants didn't exist at the time. Instead, Oregramma illecebrosa and its ilk would have gathered dry and liquid pollen from primitive, non-flowering plants.
This is another case of convergent evolution, Labandeira explained. Other studies have found that multiple groups of insects had these long mouth-parts before flowers existed, so they must have evolved specifically to suck the liquids of plants that have long gone extinct. Then, when flowers became ecologically dominant, the whole system was reinvented.
"It’s kind of like a baseball team," Labandeira said. "The positions are the same, but the players are changed. It was a different world that these insects were evolving in. So they’re serving very similar roles, but they’re completely different."

Tuesday, February 2, 2016

Yes, this prehistoric fish actually had a buzzsaw of spiraling teeth

Scientific Method / Science & Exploration

It takes an artist to capture the true weirdness of the ancient animal's face.

LOOK INTO MY TEETH AND DESPAIR.
Nicknamed the "buzzsaw shark," this 270 million-year-old creature is actually an extinct relative of the ratfish called a Helicoprion. Its bizarre tooth arrangement has confused scientists for over a century, but one artist finally got it right.
Ray Troll, whose art show about Hilicoprion has been touring the US for the past three years, has been on the front lines of scientific research about one of the strangest fossils ever found. When geologist Alexander Petrovich Karpinsky discovered the creature's tooth whorl in 1899, at first he thought it was a kind of ammonite because the teeth looked so much like the ammonite's spiral shell.
Paleo expert Brian Switek writes that it took Karpinsky a little while to realize that it was actually part of a larger animal. Over the next century, many different paleontologists offered explanations for what it might be, including a defensive formation on Helicoprion's nose, a ridge on its back, or even sticking out of its mouth like a spiky, curled tongue.
Enlarge / All the different ways that scientists have tried to 
explain where Helicoprion's spiral teeth were positioned.
Over at the Smithsonian, there's a great profile of Troll, who has done
a lot more than make art of this crazy fish. He's actually added to the
scholarship on it:
Troll’s passion, however, has served a purpose far beyond the aesthetic charm of a framed picture—it has shaped the scientific community’s knowledge of Helicoprion itself. Back in the mid-1990s, when he wrote and spoke with [paleontologist Svend Erik Bendix] Almgreen, Troll discovered that the scientist had published his hypothesis about the buzz shark’s physiology in an obscure paper in 1966. This knowledge remained hidden, lost to memory even to prominent paleontologists, until 2010, when an undergraduate student working as an intern at the Idaho Museum of Natural History got in touch with Troll.
As a result, Troll began working with paleontologist Leif Tapanila, who used used CT scans to image a whole skull of a Helicoprion—revealing that the buzzsaw shape was actually part of its lower jaw, used for slicing food and pushing it toward the back of the fish's mouth. It seems that the teeth formed in the jaw next to the topmost part of the spiral, then gradually worked their way down and back into the jaw. Once there, the teeth would be absorbed into cartilage and eventually turned into teeth again. These scans became the basis for an article published in 2013 in Biology Letters, which also included some of Troll's artwork of the buzzsaw in its rightful place.
Enlarge / Here you can see the fossils that Tapanila put into the CT scanner, along with the structure they revealed.
Royal Society
Troll's drawings and sculptures, which are still touring the US today (currently they are at the University of Oregon's Museum of Natural and Cultural History), are a reminder that paleoartists contribute a great deal to scientific discovery. Taking a whimsical approach, Troll called his show "The Buzz Sharks of Long Ago." His goofy humor is a perfect way to shine light on the truth of natural history, which is often so weird that it might as well be art.

Monday, February 1, 2016

Neanderthals were wiped out because modern humans were more ARTISTIC: Cultural lifestyle gave us an edge and helped us innovate


Monday, Feb 1st 2016
  • Researchers from Stanford University and Meiji University made the claim
  •  They used models to show a small modern human population was capable of displacing a larger Neanderthal one, due to cultural changes 
  • Art is an indicator of humans' ability to innovate, said the researchers, and once people start innovating, technology changes rapidly
  • This advanced lifestyle gave us a competitive edge, leading to extinction
ns have been blamed for killing off the Neanderthals around 30,000 years ago by breeding with them and even murdering them. 
But now experts believe it was our ancestors' artistic and innovative abilities that ultimately led to the Neanderthal's demise.
The experts believe our more advanced lifestyle gave us a cultural and competitive edge over our ancient cousins and this paved the way for their extinction.

Experts believe  Neanderthals (model pictured right) were wiped out by artistic and innovative modern humans. The study claims our more advanced lifestyle gave us a cultural and competitive edge over our ancient cousins which ultimately paved the way for their extinction
Experts believe Neanderthals (model pictured right) were wiped out by artistic and innovative modern humans. The study claims our more advanced lifestyle gave us a cultural and competitive edge over our ancient cousins which ultimately paved the way for their extinction
Researchers from Stanford University in California and Meiji University in Japan used computer models to show a small modern human population was capable of displacing a larger Neanderthal one, if they had a sufficiently large cultural advantage - such as artistic capability.
The Neanderthals faced a vicious circle because as modern humans' cultural advantages increased, their competitive advantage also increased, which in turn further boosted their cultural advantage.
The results, published in the journal Proceeding of the National Academy of Sciences, add to a growing body of evidence, that modern humans destroyed the Neanderthals.

HOW ART GAVE OUR ANCESTORS THE EDGE OVER NEANDERTHALS 

Research has shown cultural life became increasingly important for humans with childhoods becoming longer than those of Neanderthals, for instance.
Neanderthal children's teeth grew more quickly than modern human children, meaning they must have had a much reduced opportunity to learn from their parents and clan members.
Experts believe our ancestors then moved from a primitive 'live fast and die young' strategy to a 'live slow and grow old' one - making humans one of the most successful organisms on Earth.  
Elsewhere, modern humans gained new cultural abilities that allowed them to better exploit their environments and out-compete groups such as Neanderthals.
Archaeologists have found cave paintings, rock art and beads dating from after 50,000 years ago, where before then there was limited evidence of art and culture.
The study explains art is an indicator of humans' ability to innovate, and once people start innovating, technology changes rapidly.
It was likely this process that allowed humans to successfully populate the planet.
Professor Marcus Feldman, of Stanford University in California, said: 'Most archaeologists argue the advantage to modern humans lay in a higher culture level, but a sizable minority dispute this view.'
He continued that competition between the two species may have occurred when a modern human entered a region occupied by a larger Neanderthal population.
Professor Feldman said: 'We present a model for this replacement.
'Our findings shed light on the disappearance of the Neanderthals, showing that endogenous factors such as relative culture level, rather than such extrinsic factors as epidemics or climate change, could have caused the eventual exclusion of a comparatively larger population by an initially smaller one.'
Research has shown cultural life became increasingly important for humans with childhoods becoming longer than those of Neanderthals, for instance.
Neanderthal children's teeth grew much more quickly than modern human children, meaning they must have had a much reduced opportunity to learn from their parents and clan members.
Professor Feldman believes our ancestors moved from a primitive 'live fast and die young' strategy to a 'live slow and grow old' one - making humans one of the most successful organisms on the planet.
This means Neanderthals, who lived in small populations across Europe, were ill-equipped to deal with the newcomers.

The researchers said: 'Our findings shed light on the disappearance of the Neanderthals, showing that endogenous factors such as relative culture level, rather than such extrinsic factors as epidemics...could have caused the eventual exclusion [of Neanderthals]' A Neanderthal skull is pictured above
The researchers said: 'Our findings shed light on the disappearance of the Neanderthals, showing that endogenous factors such as relative culture level, rather than such extrinsic factors as epidemics...could have caused the eventual exclusion [of Neanderthals]' A Neanderthal skull is pictured above

Modern humans gained new cultural abilities (a cave painting from Montignac, France is pictured) that allowed them to better exploit their environments and out-compete groups like Neanderthals. The study explained art is an indicator of humans' ability to innovate, and once people start innovating, technology changes  rapidly
Modern humans gained new cultural abilities (a cave painting from Montignac, France is pictured) that allowed them to better exploit their environments and out-compete groups like Neanderthals. The study explained art is an indicator of humans' ability to innovate, and once people start innovating, technology changes rapidly
Elsewhere, modern humans gained new cultural abilities that allowed them to better exploit their environments and out-compete groups such as Neanderthals.
In particular, archaeologists have found evidence that big changes occurred in human society around the time the Neanderthals disappeared.

Researchers believe the artistic and inventive attributes (illustrated) of modern humans led to us out-competing Neanderthals
Researchers believe the artistic and inventive attributes 
(illustrated) of modern humans led to us out-competing Neanderthals

These include cave paintings, rock art and beads dating from after 50,000 years ago. 
Before then there was limited evidence of art and culture.
The study explained art is an indicator of humans' ability to innovate, and once people start innovating, technology changes very rapidly.
It was likely this process that allowed humans to successfully populate the planet.
However, the study will prove controversial because jewellery thought to have been made by neanderthals up to 130,000 years ago has previously been earthed.
Eight talons taken from a white-tailed eagle found at Neanderthal site in Krapina in Croatia were used to create a necklace or bracelet.
And last year, experts claimed weapons used by modern humans were no better than the Neanderthals' handiwork, signifying our direct ancestors were not technologically superior.
Dr Seiji Kadowaki, first author of this earlier study from Nagoya University, Japan, said: 'We're not so special, I don't think we survived Neanderthals simply because of technological competence.'
Early modern humans expanded the geographic area they inhabited out of Africa during a period of 55,000 to 40,000 years ago.
The researchers studied stone tools that were used by people in the Early Ahmarian culture and the Protoaurignacian culture, living in south and west Europe and west Asia around 40,000 years ago.
They used small stone points as tips for hunting weapons like throwing spears.
Researchers previously considered these to be an important innovation - one that helped the humans migrate from west Asia to Europe, where Neanderthals were living.

Previously, researchers studied stone tools that were used by people in the Early Ahmarian culture and the Protoaurignacian culture, living in south and west Europe and west Asia around 40,000 years ago. They found the human tools (pictured) were no more effective than Neanderthal-created tools of the same era
Previously, researchers studied stone tools that were used by
 people in the Early Ahmarian culture and the Protoaurignacian 
culture, living in south and west Europe and west Asia around 
40,000 years ago. They found the human tools (pictured) 
were no more effective than Neanderthal-created tools of the same era

However, the research revealed a timeline that doesn't support this theory.
If the innovation had led to the migration, evidence would show the stone points moving in the same direction as the humans.
But the study showed the possibility that the stone points appeared in Europe 3,000 years earlier than in the Levant, a historical area in west Asia.
'We looked at the basic timeline revealed by similar stone points, and it shows that humans were using them in Europe before they appeared in the Levant - the opposite of what we'd expect if the innovation had led to the humans' migration from Africa to Europe,' said Dr Kadowaki.
'Our new findings mean that the research community now needs to reconsider the assumption that our ancestors moved to Europe and succeeded where Neanderthals failed because of cultural and technological innovations brought from Africa or west Asia.'
They believe the timings imply several new scenarios about the migration of modern humans into Europe.

NEANDERTHALS WERE KILLED OFF BY MODERN DISEASES, EXPERTS CLAIM

In April last year, scientists claimed it may have been infectious diseases carried by our modern human ancestors as they migrated out of Africa that finished the Neanderthals off.
Experts studying genetic, fossil and archaeological evidence said that Neanderthals suffered from a wide range of diseases that still plague us today.
They have found evidence that suggests our prehistoric cousins would have been infected by diseases such as tuberculosis, typhoid, whooping cough, encephalitis and the common cold.
But anthropologists from Cambridge University and Oxford Brookes University said that new diseases carried by modern humans may have led to the downfall of Neanderthals.

A previous study said Neanderthals may have succumbed to infectious diseases carried to Europe by modern humans as they migrated out of Africa. Bacteria that cause tuberculosis are shown above
A previous study said Neanderthals may have succumbed to infectious diseases carried to Europe by modern humans as they migrated out of Africa. Bacteria that cause tuberculosis are shown above
They speculate that pathogens like Heliocbacter pylori, the bacteria that causes stomach ulcers, were brought to Europe by modern humans from Africa and may have infected Neanderthals, who would have been unable to fight off these new diseases.
However, Neandethals may have also helped modern humans by passing on slivers of immunity against some diseases to our ancestors when they interbred.
Dr Simon Underdown, a principal lecturer in anthropology at Oxford Brookes University and co-author of the study, said: 'As Neanderthal populations became more isolated they developed very small gene pools and this would have impacted their ability to fight off disease.
'When Homo sapiens came out of Africa they brought diseases with them.
'We know that Neanderthals were actually much more advanced than they have been given credit for and we even interbred with them.
'Perhaps the only difference was that we were able to cope with these diseases but Neanderthals could not.'

 http://arstechnica.com/

Scientific Method / Science & Exploration


Ancient hook-ups with Neanderthals left lasting effects on our health

The genetic consequences of prehistoric loving are still doing a walk of shame.



Comparison of Modern Human and Neanderthal skulls from
 the Cleveland Museum of Natural History.
WASHINGTON—Around 50,000 years ago, anatomically modern humans shacked up with some Neanderthals—and the genetic consequences are still doing a walk of shame through our generations.
The questionable interbreeding left traces of Neanderthal DNA that are linked to mood disorders, mostly depression, as well as tobacco-use disorders, skin conditions, and hypercoagulation (excessive blood clotting), according to a new study published Thursday in Science. The findings lend support to the theory that our past hominin hook-up has had a lasting influence on modern humans’ health. The data also offers hints at genetic adaptations of our ancient ancestors and, potentially, new insights into the diseases they help cause in modern humans, the authors suggest.
Having these traces of Neanderthal DNA doesn’t “doom us” to having these diseases, cautioned John Capra, bioinformaticist at Vanderbilt University and coauthor of the study. The genetic traces linked to disease in modern humans doesn’t mean that Neanderthals were stricken with those diseases either, he added. In fact, some of them could have been advantageous.
For instance, excessive blood clotting can result in strokes and heart attacks in modern humans. However, quick clotting is also a natural defense against bacteria entering a wound site, Capra explained.
He hypothesizes that some of the Neanderthal traces that linger in modern humans may have been advantageous at one point.  This would make sense, since the Neanderthals were likely highly adapted to their own environments, he added. “Perhaps spending a night or two with a Neanderthal is a relatively small price to pay for getting thousands of years of adaptations,” Capra said.
Researchers have hypothesized for some time that Neanderthal DNA—the bits that have been maintained in modern humans’ genomes, that is—can influence health. After all, Eurasian genomes contain about 1.5 to 4 percent Neanderthal DNA. But proving that the tiny fragments of ancient DNA has influence has been tricky.
For the study, Capra and colleagues harvested genetic and disease incidence data from the electronic health records of more than 28,000 adults of European ancestry. Next, the researchers compared the genetic data with that of Neanderthal genomes, looking for genetic fingerprints of the ancient hominin’s DNA in modern genomes. Then they looked for links between the presence of Neanderthal DNA and disease incidence in the adults. Capra and colleagues found a number of links, some of which seemed to be associated with sunlight exposure, they speculated. The researchers found Neanderthal DNA variations associated with skin conditions, including actinic keratosis, precancerous skin lesions linked to over exposure to the sun. There were also Neanderthal links to depression, a mood disorder that can in some cases be linked to sun exposure in modern humans, the authors point out.
Less clear, however, was the link to tobacco-use disorders, which was found in the analysis. It’s unlikely that Neanderthals were taking smoke breaks 50,000 years ago outside their caves, Capra said. But the genetic hitch in modern humans in their modern environments may confer a complex neurological trait that now creates a predisposition to nicotine addiction. Studying the link further could offer new information on understanding and even treating addiction in humans, Capra explained.
Moving forward, Capra expects that more research using big genetic and disease datasets will reveal more ancient fragments of our genome and their influence on health. After all, he said, human’s family tree is a lot more bush-like than tree-like.
Science, 2015. DOI: 10.1126/science.aad2149  (About DOIs).